Rheumatoid Arthritis (R.A.) Factor in Near Relatives of Sero-Positive and Sero-Negative Patients with Rheumatoid Arthritis

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Rheumatoid arthritis (R.A.) factor in near relatives of sero-positive and sero-negative patients with rheumatoid arthritis.

In a previous publication (de Blcourt, Polman, and de Blcourt-Meindersma, 1961), we drew attention to the familial occurrence of rheumatoid arthritis and ankylosing spondylitis, each of which shows a special hereditary factor, but we did not report on the presence or absence of the so-called rheumatic factor in probands and members of the family. The "epidemiology" of various rheumatic conditio...

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Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with different extra-articular manifestations. Among those extra-articular manifestations, there are significant cutaneous manifestations which may result in first admission to a dermatologist. In this article some specific and non-specific skin lesions of RA such as rheumatoid nodules, exacerbated nodules, rheumatoid vascu...

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Background: Previous studies showed that one of the complications of rheumatoid arthritis disease was auditory disorder. The goal of the present study was to compare the auditory status in patients with rheumatoid arthritis and healthy individuals. Methods: In the present case-control study, 30 normal persons and 60 persons with rheumatoid arthritis with mean age of 46.72 and standard deviatio...

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Differential Expression of Rheumatoid Factor-Associated Cross-Reactive Idiotypes in Iranian Seropositive and Seronegative Patients with Rheumatoid Arthritis

High levels of rheumatoid factors (RF) are detectable in serum of the majority of patients with rheumatoid arthritis (RA), but 5-10% of patients remain seronegative (SN). Despite clinical and genetic similarities between these two subsets of RA, it has been proposed that they may be regarded as distinct clinical entities. Methods: In the present study a panel of monoclonal antibodies (mAb) rec...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 1962

ISSN: 0003-4967

DOI: 10.1136/ard.21.4.339